January 24, 2022

Padres  sign Daniel Camarena

February 17, 2022

Padres  sign Tayler Scott

March 13, 2022

Padres  sign Trayce Thompson

Padres  sign Nomar Mazara

Padres  sign Jose Castillo

Padres  sign Luis Liberato

March 16, 2022

Padres  place Adrian Morejon on the injured list

March 18, 2022

Padres  place Michel Baez on the injured list

Luke Voit traded from Yankees  to Padres 

Padres  sign Travis Bergen

Padres  sign Brandon Dixon

Padres  sign Ian Krol

March 19, 2022

Padres  sign Nick Martinez as a free agent

March 20, 2022

Padres  sign Thomas Eshelman

March 26, 2022

Padres  designate James Norwood for assignment

March 28, 2022

Padres  place Drew Pomeranz on the injured list

Matt Beaty traded from Dodgers  to Padres 

March 30, 2022

James Norwood traded from Padres  to Phillies 

April 03, 2022

April 04, 2022

Padres  place Luis Garcia on the injured list

Padres  place Mike Clevinger on the injured list

April 06, 2022

Victor Caratini traded from Padres  to Brewers 

April 07, 2022

Padres  place Fernando Tatis Jr. on the injured list

Padres  designate Kyle Tyler for assignment

April 12, 2022

Padres  designate Javy Guerra for assignment

April 14, 2022

Padres  sign Daniel Camarena

April 15, 2022

Padres  place Blake Snell on the injured list

April 16, 2022

Javy Guerra traded from Padres  to Rays 

April 21, 2022

Padres  place Pierce Johnson on the injured list

April 28, 2022

Padres  place Wil Myers on the injured list

May 03, 2022

Padres  sign Yusmeiro Petit

May 07, 2022

Padres  place Tim Hill on the injured list

May 09, 2022

Padres  place Matt Beaty on the injured list

Padres  sign Shogo Akiyama

May 10, 2022

Padres  designate Trayce Thompson for assignment

May 13, 2022

Padres  sign Robinson Cano as a free agent

May 14, 2022

Trayce Thompson became a free agent

May 22, 2022

Padres  place Mike Clevinger on the injured list

June 02, 2022

Robinson Cano became a free agent

June 03, 2022

Padres  place Wil Myers on the injured list

June 06, 2022

Padres  designate Kyle Tyler for assignment

June 07, 2022

Padres  place Robert Suarez on the injured list

June 11, 2022

Padres  place Adrian Morejon on the injured list

Padres  place Mike Clevinger on the injured list

June 17, 2022

Padres  place Matt Beaty on the injured list

Padres  place Joe Musgrove on the injured list

June 23, 2022

Padres  place Adrian Morejon on the injured list

June 26, 2022

Padres  place Steven Wilson on the injured list

June 30, 2022

Padres  designate Sergio Alcantara for assignment

July 03, 2022

Padres  designate Kyle Tyler for assignment

July 08, 2022

Padres  place Jurickson Profar on the injured list

July 09, 2022

Padres  place Craig Stammen on the injured list

July 10, 2022

Robinson Cano traded from Padres  to Braves 

July 26, 2022

Padres  place MacKenzie Gore on the injured list

August 01, 2022

August 02, 2022

Eric Hosmer traded from Padres  to Red Sox 

Brandon Drury traded from Reds  to Padres 

August 13, 2022

Padres  designate Tayler Scott for assignment

August 15, 2022

Padres  place Tayler Scott on the injured list

August 19, 2022

Padres  sign Brandon Kintzler

August 20, 2022

Padres  designate Nomar Mazara for assignment

August 23, 2022

Padres  release Nomar Mazara

August 26, 2022

Padres  place Jorge Alfaro on the injured list

September 05, 2022

Padres  place Brandon Drury on the injured list

September 09, 2022

Padres  designate Cam Gallagher for assignment

September 10, 2022

Padres  designate Matt Beaty for assignment

September 11, 2022

Padres  designate Tayler Scott for assignment

September 27, 2022

Padres  designate Luis Liberato for assignment

October 05, 2022

Padres  place Mike Clevinger on the injured list

November 06, 2022

Josh Bell became a free agent

Sean Manaea became a free agent

Brandon Drury became a free agent

Craig Stammen became a free agent

Pierce Johnson became a free agent

Mike Clevinger became a free agent

November 07, 2022

Robert Suarez became a free agent

Wil Myers became a free agent

Jurickson Profar became a free agent

November 10, 2022

Nick Martinez became a free agent

November 17, 2022

Padres  sign Robert Suarez as a free agent

November 18, 2022

Jorge Alfaro became a free agent

November 22, 2022

Padres  sign Nick Martinez as a free agent

December 03, 2022

Padres  sign Efrain Contreras as a free agent

December 08, 2022

Padres  sign Xander Bogaerts as a free agent