January 04, 2021

Nationals  sign Luis Avilan

January 06, 2021

Nationals  sign Alberto Baldonado

January 09, 2021

Nationals  sign Kyle Schwarber as a free agent

January 23, 2021

Nationals  sign Ryan Zimmerman as a free agent

January 26, 2021

Nationals  sign Brad Hand as a free agent

January 27, 2021

Nationals  sign Jon Lester as a free agent

February 03, 2021

Nationals  sign Hernan Perez

Nationals  sign Alex Avila as a free agent

February 04, 2021

Nationals  sign Humberto Arteaga

February 17, 2021

Nationals  sign Gerardo Parra as a free agent

Nationals  sign T.J. McFarland

February 23, 2021

Nationals  sign Justin Miller as a free agent

February 26, 2021

Nationals  sign Andres Machado as a free agent

March 22, 2021

Nationals  sign Kyle Lobstein as a free agent

March 29, 2021

Nationals  sign T.J. McFarland as a free agent

April 06, 2021

Nationals  place Josh Bell on the injured list

Nationals  place Jon Lester on the injured list

Nationals  place Kyle Schwarber on the injured list

Nationals  place Jordy Mercer on the injured list

Nationals  place Yan Gomes on the injured list

Nationals  place Will Harris on the injured list

Nationals  place Alex Avila on the injured list

Nationals  place Patrick Corbin on the injured list

Nationals  place Brad Hand on the injured list

Nationals  place Josh Harrison on the injured list

Nationals  sign Jonathan Lucroy as a free agent

April 12, 2021

Nationals  designate Jonathan Lucroy for assignment

April 16, 2021

Nationals  place Luis Avilan on the injured list

April 18, 2021

Nationals  place Wander Suero on the injured list

Nationals  place Stephen Strasburg on the injured list

April 20, 2021

Nationals  place Juan Soto on the injured list

April 30, 2021

Nationals  place Luis Avilan on the injured list

May 04, 2021

Nationals  designate Hernan Perez for assignment

May 17, 2021

Nationals  place Patrick Corbin on the injured list

May 19, 2021

Nationals  place Tanner Rainey on the injured list

Nationals  place Erick Fedde on the injured list

May 23, 2021

Nationals  place Victor Robles on the injured list

Nationals  place Will Harris on the injured list

June 02, 2021

Nationals  place Stephen Strasburg on the injured list

June 04, 2021

Nationals  sign Josh Rogers

June 08, 2021

Nationals  place Austin Voth on the injured list

June 12, 2021

Nationals  place Daniel Hudson on the injured list

Nationals  place Will Harris on the injured list

June 15, 2021

Nationals  place Max Scherzer on the injured list

June 18, 2021

Nationals  place Andrew Stevenson on the injured list

June 20, 2021

Nationals  designate Ben Braymer for assignment

June 22, 2021

Nationals  place Kyle Finnegan on the injured list

June 27, 2021

Nationals  place Erick Fedde on the injured list

June 29, 2021

Nationals  place Tanner Rainey on the injured list

Nationals  designate Justin Miller for assignment

July 02, 2021

Nationals  place Jordy Mercer on the injured list

July 03, 2021

Nationals  place Kyle Schwarber on the injured list

Nationals  place Alex Avila on the injured list

Nationals  designate Humberto Arteaga for assignment

Alcides Escobar traded from Royals  to Nationals 

July 08, 2021

Nationals  place Joe Ross on the injured list

July 10, 2021

Nationals  place Yan Gomes on the injured list

Nationals  designate Kyle Lobstein for assignment

July 11, 2021

Nationals  place Kyle McGowin on the injured list

July 13, 2021

Kyle Lobstein traded from Nationals  to Brewers 

July 16, 2021

Nationals  sign Rene Rivera as a free agent

July 24, 2021

Nationals  place Jordy Mercer on the injured list

July 29, 2021

Nationals  place Daniel Hudson on the injured list

Nationals  place Trea Turner on the injured list

Nationals  place Austin Voth on the injured list

Nationals  place Alex Avila on the injured list

Kyle Schwarber traded from Nationals  to Red Sox 

July 30, 2021

August 03, 2021

Nationals  place Rene Rivera on the injured list

August 11, 2021

Nationals  place Stephen Strasburg on the injured list

August 14, 2021

Nationals  release Rene Rivera

August 15, 2021

Nationals  place Joe Ross on the injured list

August 22, 2021

Nationals  designate Javy Guerra for assignment

August 23, 2021

Nationals  place Joe Ross on the injured list

August 24, 2021

Nationals  designate Jefry Rodriguez for assignment

Javy Guerra became a free agent

September 03, 2021

Nationals  place Kyle McGowin on the injured list

Nationals  release Starlin Castro

September 04, 2021

Nationals  place Kyle McGowin on the injured list

September 05, 2021

Nationals  place Gerardo Parra on the injured list

September 13, 2021

Nationals  designate Adrian Sanchez for assignment

September 23, 2021

Nationals  designate Jakson Reetz for assignment

October 02, 2021

Nationals  place Josh Rogers on the injured list

October 03, 2021

Nationals  place Luis Garcia on the injured list

November 02, 2021

Nationals  sign Sean Nolin

November 03, 2021

Ryan Zimmerman became a free agent

Luis Avilan became a free agent

Alex Avila became a free agent

Jordy Mercer became a free agent

Gerardo Parra became a free agent

November 08, 2021

Nationals  sign Jefry Rodriguez

November 10, 2021

Nationals  sign Adrian Sanchez

November 24, 2021

Nationals  sign Victor Arano

November 25, 2021

Nationals  sign Luis Avilan

November 30, 2021

Wander Suero became a free agent

Mike Ford became a free agent

Ryne Harper became a free agent

Nationals  sign Cesar Hernandez as a free agent

December 12, 2021

Nationals  sign Dee Strange-Gordon

Nationals  sign Maikel Franco